The goal of this session is to discuss the medicinal chemistry (including neurotransmitters involved in nociception), pharmacokinetics, pharmacology, and pharmacotherapeutics of opioids (including antagonists) and nonopioid analgesics, and adjuvants in an evidence-based framework. Nonopioid analgesics to be discussed include acetaminophen, salicylates, and nonsteroidal anti-inflammatory drugs. Adjuvants include corticosteroids, anticonvulsants (including gabapentinoids), serotonin-norepinephrine reuptake inhibitors, and topical analgesics. Special considerations for treating children, older adults, and persons with substance abuse disorders will be covered. This session will also include comparisons and contrasts of the opioid analgesics, as well as equianalgesic conversion methods, and monitoring parameters.
Instructional Strategies: Lecture/Discussion, Team-based Learning, Online learning modules, 8 hours
Author: Scott Strassels, MD
School: Ohio State University
Fishman SM, Carr DB, Hogans B, Cheatle M, Gallagher RM, Katzman J, Mackey S, Polomano R, Popescu A, Rathmell JP, Rosenquist RW, Tauben D, Beckett L, Li Y, Mongoven JM, Young HM. Scope and Nature of Pain- and Analgesia-Related Content of the United States Medical Licensing Examination (USMLE). Pain Med. 2018 Mar 1;19(3):449-459. doi: 10.1093/pm/pnx336. PubMed PMID: 29365160; PubMed Central PMCID: PMC6057520. Full text, no login required: https://academic.oup.com/painmedicine/article-pdf/19/3/449/25332233/pnx336.pdf
The Pain Management Core Curriculum for European Medical Schools – Version June 2013 by EFIC (Europe Against Pain). Full text, no login required: https://europeanpainfederation.org/wp-content/uploads/2018/10/CoreCurriculumPainManagement-EFIC-June-2013_FINAL1.pdf
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