FOM: Journal Club Workshop 8/14/2024

Biostatistics, Epidemiology/Population Health, & Interpretation of the Medical Literature

• Study design, types and selection of studies (includes dependent/independent variables)
  • Analytical studies: interventional
    • randomized control trial
• Study interpretation, drawing conclusions from data
  • Chance
  • Interpretation of graphs/tables and text
  • Bias, confounding, and threats to validity
  • Internal vs external validity
  • Statistical vs clinical significance; clinical and surrogate outcome/end point
• Clinical decision making, interpretation and use of evidence-based data and recommendation

Multisystem Processes & Disorders

• Nutrition
  • Obesity

AAMC Core Entrustable Professional Activities for Entering Residency

• EPA 7: Form Clinical Questions and Retrieve Evidence to Advance Patient Care

FOM
August 14, 2024

ANNOUNCEMENTS:

In Class Session: 11 am -12 pm
TOPIC: How to Read a Research Article: Journal Club Workshop

FACULTY: Paul Lecat, M.D., Faculty, Ph.D., & Heather McEwen, MLIS, MS

LEARNING OBJECTIVES:

By the end of this session, students will be able to:

• List the components of research articles and explain how physicians can apply basic and clinical research to patient care.
• List some common pitfalls often missed in research articles and discuss why literature evaluation is a necessary skill for physicians.
• Answer questions about the components of a research article discussed and discuss how the article could be applied to patient care
• Discuss the common components of a journal club presentation.
• Practice critically analyzing a research article focused upon the treatment of substance abuse disorder
• At the completion of this assignment, students will be able to: Apply obesity research to diagnosis and/or treatment of patients
• At the completion of this in-class exercise, students will be able to:  compose their own list of strengths and weaknesses for their research article

PRIOR To CLASS: Read the assigned article

ASSIGNED ARTICLE: 

Rubino DM, Greenway FL, Khalid U, O'Neil PM, Rosenstock J, Sørrig R, Wadden TA, Wizert A, Garvey WT; STEP 8 Investigators. Effect of Weekly Subcutaneous Semaglutide vs Daily Liraglutide on Body Weight in Adults With Overweight or Obesity Without Diabetes: The STEP 8 Randomized Clinical Trial. JAMA. 2022 Jan 11;327(2):138-150. doi: 10.1001/jama.2021.23619. PMID: 35015037; PMCID: PMC8753508.

Article is also available via PubMed Central

SUPPLEMENTAL INFORMATION:

• KFF Health Tracking Poll May 2024: The Public’s Use and Views of GLP-1 Drugs

ASSESSMENT: None

SESSION RESOURCES: See CANVAS for the the link to the article.