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Using a RCT - FRISBEE: Validity of Research
||Equivalence to your patient
Xiong GL, Adams J. FRISBEE: Does the study fly in the face of evidence-based medicine? The Journal of Family Practice. 2007 Dec;6(12). Available from: https://www.mdedge.com/psychiatry/article/62967/frisbee-does-study-fly-face-evidence-based-medicine
FRISBEE is great for randomized control trials. See one of the links below if you are using a systematic review. They websites have systematic review evaluation worksheets.
Help to Determine the Validity for non-RCT Research Articles or Clinical Guidelines
Appraisal tool for Cross-Sectional Studies (AXIS)
See page 3. Developed by: Downes MJ, Brennan ML, Williams HC, Dean RS. Development of a critical appraisal tool to assess the quality of cross-sectional studies (AXIS). BMJ Open. 2016;6(12):e011458. Published 2016 Dec 8. doi:10.1136/bmjopen-2016-011458 Available at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5168618/
Critical Appraisal Tools (Validity) - Joanna Briggs Institute
This site has worksheets to determine validity of articles such as case series, case control studies, case reports, etc.
Evidence-Based Practice: Appraise - Worksheets
Duke University Medical Center Library & Archives: This site has a worksheet that can help you check the validity of systematic reviews. FRISBEE is designed for randomized control trials.
Number Needed to Treat (NNT)
- NNT = number of patients needed to treat in order to prevent one bad outcome
- NNT = 1/ARR
- ARR = CER - EER
- Number Needed to Harm (NNH) is calculated the same way as NNT
- If a research study had non-statistically significant results, it is not appropriate to calculate NNT.
- Should be calculated for binary results (MIs versus no MIs).
- Students should state if is not appropriate to calculate NNT.
- NNT for a study is always for a specific time period.
- NNT does not consider baseline risk.
- More information - http://www.cebm.net/number-needed-to-treat-nnt/ and https://www.med.uottawa.ca/sim/data/Number_Needed_to_Treat_e.htm