NEOMED Library: Journal Club Presentation Resources (Statistics Help): Meta-Analyses & Systematic Reviews

Evaluation Tools

AHRQ: Spotting a Bad Meta-Analysis
AHRQ YouTube video
Are Network Meta-Analysis More Prone to Unreliable Conclusions?
Improving Medical Statistics and the Interpretation of Clinical Trials
Development of AMSTAR: A Measurement Tool to Assess the Methodological Quality of Systematic Reviews
BMC Medical Research Methodology article
How to Review a Meta-analysis Article
Russo MW. How to review a meta-analysis. Gastroenterol Hepatol (N Y). 2007;3(8):637-42.
Individual Participant Data (IPD) Meta-analyses of Randomised Controlled Trials: Guidance on Their Use
Tierney JF, Vale C, Riley R, et al. Individual participant data (IPD) meta-analyses of randomised controlled trials: guidance on their use. PLoS Med. 2015;12(7):e1001855.
Jadad Score
Berger VW, Alperson SY. A general framework for the evaluation of clinical trial quality. Rev Recent Clin Trials. 2009;4(2):79-88. doi:10.2174/157488709788186021
Limitations of Meta-analysis: Overview
Improving Medical Statistics and the Interpretation of Clinical Trials
Living Systematic Reviews: Towards Real-time Evidence for Health-care Decision-making
BMJ Blog
By Chris Mavergames and Julian Elliott
Meta-Analysis: Principles and Procedures article
Egger M. Meta-analysis: principles and procedures. BMJ 1997;315:1533.
Network Meta-Analysis
Li T, Puhan MA, Vedula SS, Singh S, Dickersin K. Network meta-analysis-highly attractive but more methodological research is needed. BMC Med. 2011;9:79.
The Newcastle-Ottawa Scale (NOS) for Assessing the Quality of Nonrandomised Studies in Meta-analyses
GA Wells, B Shea, D O'Connell, J Peterson, V Welch, M Losos, P Tugwell. Department of Epidemiology and Commuunity Medicine, University of Ottawa
Overview of Meta-Analysis and Methods
greatdoctorstv YouTube video of Gordon Guyatt, M.D., M.Sc.
Preferred Reporting Items for Systematic Review and Meta-analysis Protocols (PRISMA-P) 2015: Elaboration and Explanation
Shamseer L, Moher D, Clarke M, et al. Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015: elaboration and explanation. BMJ. 2015;349:g7647.
Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement
Annals of Internal Medicine article
Problems with Meta-Analysis Methods
greatdoctorstv YouTube video of Gordon Guyatt, M.D., M.Sc.
Tips for Learners of Evidence-Based Medicine: 4. Assessing Heterogeneity of Primary Studies in Systematic Reviews and Whether to Combine their Results
Hatala R, Keitz S, Wyer P, Guyatt G. Tips for learners of evidence-based medicine: 4. Assessing heterogeneity of primary studies in systematic reviews and whether to combine their results. CMAJ. 2005;172(5):661-5.
Traditional Reviews, Meta-analyses and Pooled Analyses in Epidemiology
Blettner M, Sauerbrei W, Schlehofer B, Scheuchenpflug T, Friedenreich C. Traditional reviews, meta-analyses and pooled analyses in epidemiology. Int J Epidemiol. 1999;28(1):1-9. Article discusses the different types of meta-analyses.
Traditional Reviews vs. Systematic Reviews tutorial
Students 4 Best Evidence

Understanding the Statistics

5 Key Things to Know About Meta-Analysis
Hilda Bastian - Absolutely Maybe
Another 5 Things to Know About Meta-Analysis
Bastian H. Absolutely Maybe : Evidence and Uncertainties about Medicine and Life PLOS blog.
Applying a Meta-analysis to Daily Clinical Practice
Miser WF. Applying a meta-analysis to daily clinical practice. J Am Board Fam Pract. 2000;13(3):201-10.
Are Network Meta-analysis More Prone to Unreliable Conclusions?
Improving Medical Statistics and the Interpretation of Clinical Trials
Cautionary Tales in the Interpretation of systematic Reviews of Therapy Trials
Scott I, Greenberg P, Poole P, Campbell D. Cautionary tales in the interpretation of systematic reviews of therapy trials. Intern Med J. 2006;36(9):587-99.
Fixed Effects and Random Effects Models
Terry Shaneyfelt, M.D.
Forest Plot at a Glance tutorial
Students 4 Best Evidence
Funnel Plots
Heterogeneity: Assessing Heterogeneity in Meta-Analysis: Q Statistic or I2 Index?
University of Connecticut - Tania Huedo-Medina, et al.
How to Interpret a Forest Plot YouTube video
Terry Shaneyfelt, M.D.
How to Read a Forest Plot in a Meta-analysis
Sedgwick P. How to read a forest plot in a meta-analysis. BMJ 2015;351:h4028
Individual Patient-level and Study-level Meta-analysis for Investigating Modifiers of Treatment Effect
Teramukai S, Matsuyama Y, Mizuno S, Sakamoto J. Individual patient-level and study-level meta-analysis for investigating modifiers of treatment effect. Jpn J Clin Oncol. 2004;34(12):717-21. Discusses the difference between individual patient-level and study-level meta-analyses.
Living Systematic Reviews
The Cochrane Library
Measuring Inconsistency in Meta-Analyses
Higgins JP, Thompson SG, Deeks JJ, Altman DG. Measuring inconsistency in meta-analyses. BMJ. 2003;327(7414):557-60.
Meta-analyses: Heterogeneity and Subgroup Analysis
Sedgwick P. Meta-analyses: heterogeneity and subgroup analysis. BMJ. 2013;346:f4040.
Meta-analyses: How to Read a Funnel Plot
Sedgwick P. Meta-analyses: how to read a funnel plot. BMJ. 2013;346:f1342.
Meta-analyses: Tests of Heterogeneity
Sedgwick P. Sample size: how many participants are needed in a trial?. BMJ. 2012;344:e3971.
Meta-Analysis
Handbook of Biological Statistics
John H. McDonald
Network Meta-Analysis
Li T, Puhan MA, Vedula SS, Singh S, Dickersin K. Network meta-analysis-highly attractive but more methodological research is needed. BMC Med. 2011;9:79.
What is a Prospective Meta-Analysis?
Cochrane Prospective Meta-Analysis Methods Group
What is Heterogeneity?
YouTube video by Terry Shaneyfelt, M.D.

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Journal Club Presentation Resources (Statistics Help): Meta-Analyses & Systematic Reviews

Evaluation Tools

Understanding the Statistics

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