NEOMED Library: Journal Club Presentation Resources (Statistics Help): Blinding / Randomization / Subgroup Analysis

Blinding

Allocation Concealment Is Often Confused With Blinding
EBM Teacher Blog
Terry Shaneyfelt, M.D.
Blinding in Clinical Trials and Other Studies
Day SJ, Altman DG. Blinding in clinical trials and other studies. BMJ. 2000;321:504.
Double Dummy Technique
On Biostatistics and Clinical Trials Blog
Double Dummy Trials
Sedgwick P. Double dummy trials. BMJ. 2011;343:d7294.
Blinding in Clinical Trials: Seeing the Big Picture
Monaghan TF, Agudelo CW, Rahman SN, et al. Blinding in Clinical Trials: Seeing the Big Picture. Medicina (Kaunas). 2021;57(7):647. Published 2021 Jun 24. doi:10.3390/medicina57070647
Blinding: Who, What, When, Why, How?
Karanicolas PJ, Farrokhyar F, Bhandari M. Practical tips for surgical research: blinding: who, what, when, why, how?. Can J Surg. 2010;53(5):345-348.
Threats to Blinding Video
NEJM Evidence

Subgroup Analyses: Subpar or Sublime? Video
NEJM Evidence
When to believe a subgroup analysis: revisiting the 11 criteria
Farrokhyar F, Skorzewski P, Phillips MR, Garg SJ, Sarraf D, Thabane L, Bhandari M, Chaudhary V; Retina Evidence Trials InterNational Alliance (R.E.T.I.N.A.) Study Group. When to believe a subgroup analysis: revisiting the 11 criteria. Eye (Lond). 2022 Nov;36(11):2075-2077. doi: 10.1038/s41433-022-01948-0. Epub 2022 Jan 31. PMID: 35102244; PMCID: PMC9582008.

An Overview of Randomization Techniques: An Unbiased Assessment of Outcome in Clinical Research
Suresh K. An overview of randomization techniques: An unbiased assessment of outcome in clinical research. Journal of Human Reproductive Sciences. 2011;4(1):8-11.
Why Randomize?
Yale University Institution for Social and Policy Studies
Allocation Concealment: the Key to Effective Randomisation
Students 4 Best Evidence
Randomization in Clinical Trials Permuted Blocks and Stratification
Broglio K. Randomization in Clinical Trials: Permuted Blocks and Stratification. JAMA. 2018 Jun 5;319(21):2223-2224. doi: 10.1001/jama.2018.6360. Erratum in: JAMA. 2022 Mar 1;327(9):880. PMID: 29872845.
Designing a research project: randomised controlled trials and their principles
Kendall JM. Designing a research project: randomised controlled trials and their principles. Emerg Med J. 2003 Mar;20(2):164-8. doi: 10.1136/emj.20.2.164. PMID: 12642531; PMCID: PMC1726034.