NEOMED Library: Journal Club Presentation Resources (Statistics Help): General Statistics / Incidence & Prevalence / Hypothesis Testing

General Statistical Topics

Evaluating a Therapy Study
MUSM Libraries
Interpreting the Results of Secondary End Points and Subgroup Analyses in Clinical Trials
Freemantle N. Interpreting the results of secondary end points and subgroup analyses in clinical trials: should we lock the crazy aunt in the attic?. BMJ. 2001;322(7292):989-91. Article freely available via PubMed Central
Know Your Chances: Understanding Health Statistics e-book
Know Your Chances: Understanding Health Statistics
Steven Woloshin, MD, MS, Lisa M. Schwartz, MD, MS, and H. Gilbert Welch, MD, MPH.
Berkeley (CA): University of California Press; 2008.
Mean, Median, Mode
Khan Academy
Placebo versus Best-Available-Therapy Control Group in Clinical Trials for Pharmacologic Therapies
Mario Castro. Placebo versus best-available-therapy control group in clinical trials for pharmacologic therapies. Proceedings of the American Thoracic Society. 2007;4(7):570-573.
Clinical Outcomes and Endpoints
Endpoint Adjudication Blog
Sample Size: How Many Participants are Needed in a Trial?
Sedgwick P. Sample size: how many participants are needed in a trial? BMJ. 2013;346:f1041.
Sampling and Normal Distribution
Howard Hughes Medical Institute BioInteractive
Standard Deviations and Standard Errors
Altman DG, Bland JM. Standard deviations and standard errors. BMJ. 2005;331(7521):903.
Statistics Review 1: Presenting and Summarising Data
Whitley E, Ball J. Statistics review 1: presenting and summarising data. Crit Care. 2002;6(1):66-71.
Statistics Review 2: Samples and Populations
Whitley E, Ball J. Statistics review 2: samples and populations. Crit Care. 2002;6(2):143-8.
Statistics review 3: hypothesis testing and P values
Whitley E, Ball J. Statistics review 3: hypothesis testing and P values. Crit Care. 2002 Jun;6(3):222-5. doi: 10.1186/cc1493. Epub 2002 Mar 18. Erratum in: Crit Care. 2003 Feb;7(1):15. PMID: 12133182; PMCID: PMC137449.
Statistics Review 4: Sample Size Calculations
Whitley E, Ball J. Statistics review 4: sample size calculations. Crit Care. 2002;6(4):335-41.
Statistics Review 5: Comparison of Means
Whitley E, Ball J. Statistics review 5: Comparison of means. Crit Care. 2002;6(5):424-8.
Six Red Flags for Suspect Work.
Begley CG. Six red flags for suspect work. Nature. 2013;497(7450):433-4.
Preclinical work.
Reproducibility: Two More Red Flags for Suspect Work
McDermott JE. Reproducibility: two more red flags for suspect work. Nature. 2013;499(7458):284.
The Random Allocation Process: Two Things You Need to Know
Dettori J. The random allocation process: two things you need to know. Evid Based Spine Care J. 2010;1(3):7-9. doi:10.1055/s-0030-1267062
Seeing Theory: A Visual Introduction to Probability and Statistics
Daniel Kunin - Brown University
Composite Outcomes
Teachers of Evidence-Based Health Care
Switched Outcomes

Prevalence & Incidence

Basic Statistics: About Incidence, Prevalence, Morbidity, and Mortality - Statistics Teaching Tools
Department of Health New York state
Quantifying Disease in Populations
The BMJ
Incident vs. Prevalent Cases and Measures of Occurrence
Alexander L, Lopes B, Ricchetti-Masterson K, Yeatts KB. Incident vs. Prevalent Cases and Measures of Occurrence . ERIC Notebook. 2nd ed. University of North Carolina, School of Public Health, Department of Epidemiology, Epidemiologic Research and Information Center
Prevalence vs. Incidence: What is the Difference?
Students 4 Best Evidence

Hypothesis Testing & P Values

Confidence Interval or P-Value?: Part 4 of a Series on Evaluation of Scientific Publications
Du Prel J-B, Hommel G, Röhrig B, Blettner M. Confidence interval or P-value?: part 4 of a series on evaluation of scientific publications. Dtsch Arztebl Int. 2009;106(19):335-339.
How Results Are Presented (1): P-values, CIs and Significance
(2007), How results are presented (1): p-values, CIs and significance. Prescriber, 18: 33–37.
How to Read a Paper: Statistics for the Non-statistician. II: “Significant” Relations and their Pitfalls
Greenhalgh T. How to read a paper. Statistics for the non-statistician. II: "Significant" relations and their pitfalls. BMJ. 1997;315(7105):422-5.
P-Values
HealthKnowledge
P Values or Confidence Intervals?
Sedgwick P. P values or confidence intervals? BMJ. 2013;346:f3212.
Science Isn’t Broken: It’s just a hell of a lot harder than we give it credit for
FiveThirtyEightScience blog by By Christie Aschwanden.
Scientific Method: Statistical Errors
Nuzzo R. Scientific method: statistical errors. Nature. 2014;506(7487):150-2.
Statistics Review 3: Hypothesis Testing and P Values
Whitley E, Ball J. 2002. Statistics review 3: hypothesis testing and P values. Crit Care. 2002;6(3):222-5.
What is a P Value?
Sedgwick P. What is a P value? BMJ. 2102;345:e7767.

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Journal Club Presentation Resources (Statistics Help): General Statistics / Incidence & Prevalence / Hypothesis Testing

General Statistical Topics

Prevalence & Incidence

Hypothesis Testing & P Values